منابع مشابه
Enzymic synthesis of N-acetyl-D-mannosamine.
As repor ted earlier 1, an e n z y m e purif ied f rom Clostridium per#ingens (N-ace ty lneuramin ic acid aldolase; NaNaldolase) ca ta lyzes t he following reversible reac t ion: p y r u v a t e + N-acetyl-Dm a n n o s a m i n e (N-AcMm) ~ N-ace t y l neu rami n i c acid (sialic acid). The recogni t ion of N A c M m as a na tu ra l l y occurr ing suga r leads to t h e ques t ion of t he m e c h...
متن کاملMetabolism of Exogenous Diacylglycerols by Human Platelets*
The metabolism of exogenous [3H]diacylglycerols by intact human platelets was studied in order to examine: 1) the metabolic fate of these second messengers in an intact cell, 2) the effect of diacylglycerol kinase and diacylglycerol lipase inhibitors on this metabolism, 3) the effect of agonist stimulation on metabolism, and 4) the dependence of metabolism on diacylglycerol chain length. When 2...
متن کاملAlterations in the D-glucuronic Acid Pathway and Drug Metabolism W Exogenous Compounds
Treatment of guinea-pigs with disulfiram for 8 days resulted in a significant enhancement of the in vitro activities of the N-demethylation of aminopyrine and the glucuronyl conjugation of p-mtrophenol. This increase was accompanied by an induction of liver growth and an increase in microsomal protein content. It might be concluded that disulfiram has inductive properties with respect to drug m...
متن کاملAlterations in the D-glucuronic Acid Pathway and Drug Metabolism W Exogenous Compounds
Treatment of guinea-pigs with disulfiram for 8 days resulted in a significant enhancement of the in vitro activities of the N-demethylation of aminopyrine and the glucuronyl conjugation of p-mtrophenol. This increase was accompanied by an induction of liver growth and an increase in microsomal protein content. It might be concluded that disulfiram has inductive properties with respect to drug m...
متن کاملAlterations in the D-glucuronic Acid Pathway and Drug Metabolism W Exogenous Compounds
Treatment of guinea-pigs with disulfiram for 8 days resulted in a significant enhancement of the in vitro activities of the N-demethylation of aminopyrine and the glucuronyl conjugation of p-mtrophenol. This increase was accompanied by an induction of liver growth and an increase in microsomal protein content. It might be concluded that disulfiram has inductive properties with respect to drug m...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1970
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)63041-8